> What I've Learned. Why We Get Fat AND Hungry | (Biology of Weight Gain & Low-Carb ). YouTube, <https://www.youtube.com/watch?v=KHaCKudtVi0>. Accessed 16 Aug. 2021. # Why we get Fat AND Hungry | (Biology of Weight Gain & Low-Carb ) > This video explains the, history, data and Biology behind what really matters to weight gain & The vicious cycle created by a bad diet. - Donaldson, *Strong Medicine* - Calories in / out is poorly justified - Low carb is not new: - 1797: John Rollo treated diabetes with a low carb diet - 1971: Young study: LCHF diet leads to more weight loss - 1977: food pyramid - Not calories, but **hormones** cause weight gain - Especially insulin, the fat storage hormone - Glucose in the blood damages bodily functions through glycation - That's why it is broken down and stored as triglycerides in your body fat - High serum insulin level prevents you from breaking down fat tissue because hormon sensitive lypase is sensitive to insulin - High blood sugar and insulin keep us fat and hungry - Edward Adolph in 1940 couldn't trick his lab rats to take in more nutrients than usual - If you feed your body properly, it will regulate consumption for you - In 1960, Ethan Sims tried to overfeed human test subjects - He could get them to eat 7,000 excess calories of carbs, but 800 calories of fat took a lot of effort - Fiber reduces the rate of carbohydrate absorption, reducing the insulin response - As hunter-gatherers, we used to get between 100 and 300g of fibers a day; now, it's about 15g